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Thyroid Study
by Peggy Turner
Hypothyroidism
is the most common, heritable endocrine disorder of dogs. Up to 80% of cases
result from an autoimmune disease that progressivley destroys the thyroid
gland, called autoimmune thyroiditis. Once this disease has destroyed more
than 75% of the thyroid gland, clinical signs of hypothyroidism (low thyroid
function)appear. Because the thyroid gland regulates metabolism of all body
cellular functions, hypothyroidism can produce a wide range of clinical
signs, causing neuromuscular problems, reproductive disorders, eye diseases,
and more. Our dogs can have chronic infections, incontinence, infertility,
absence of heat cycles, dying and stillborn pups, dry eye, and bleeding
disorders. Dogs can also show unprovoked aggresssion, exhibit fearfulness
or anxiety, or have seizures. Individuals genetically susceptible to autoimmune
thyroid disease may also become more prone to immune mediated disease. This
is a disease that has significant implications for breeding stock, and is
certainly cause for serious concern to anyone who owns and loves a Kerry
Blue Terrier.
Presently Dr. Lorna Kennedy at the University of Manchester in England is
trying to find the gene that causes Autoimmune Thyroiditis in Kerries. If
the gene is located, then a test can be developed that will allow breeders
to test for that gene before breeding their Kerry. By NOT breeding affected
Kerries, Autoimmune Thyroiditis can be eliminated from the gene pool of
our wonderful breed. This is a project that is crucial to the future health
of our Kerries.
The
Kerry Blue Terrier Foundation, in affiliation with Dr. Jean Dodds of California,
have been given an opportunity to help with this research. We
are presently looking for 50 Kerries to participate by donating blood. (A
copy of the dog's pedigree must be included.) The samples will then
be shipped overnight to Dr. Dodds at Hemopet who will process the blood
and forward it to Dr. Kennedy in England. In exchange for each Kerry that
gives a blood sample, Dr. Dodds will be providing their owners with a complete
thyroid panel, free of charge.(a $65 value!)
For the purposes of this study a copy of each dogs pedigree would also be
needed, from any registry. With your help, this research has a great chance
of success, and we can all gain by protecting our Kerries, for many generations
to come. We are asking that anyone that plans to send blood please contact
Peggy Turner at peggyturner@verizon.net
so that we may keep track of how many donors we have. And thank you for
helping a great breed become healthier.
Please print
the submittal form and take it to your vet to draw a blood sample.
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